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DISEASES TARGETED BY STEM CELL TREATMENTS

Stem cell therapy has already been used in the treatment of these diseases*:

Cancers

• Acute lymphoblastic leukemia (ALL)
• Acute myelogenous leukemia (AML)
• Burkitt's lymphoma
• Chronic myelogenous leukemia (CML)
• Juvenile chronic myelogenous leukemia (JCML)
• Juvenile myelomonocytic leukemia
• Chronic lymphocytic leukemia (CLL)
• Liposarcoma
• Myelodysplastic syndrome (MDS)
• Chronic myelomonocytic leukemia (CMML)
• Refractory anemia with excess blasts in transformation (RAEB-t)
• Neuroblastoma
• Non-Hodgkin's lymphoma
• Hodgkin's disease
• Retinoblastoma

Hemoglobinopathies and Blood Disorders

• Sickle-cell anemia
• b-Thalassemia (Cooley's anemia)

Other diseases

• Evans syndrome
• Familial erythrophagocytic hemophagocytic
• Langerhans cell histiocytosis
• Osteopetrosis

Bone Marrow Failure Syndromes

• Aplastic anemia
• Blackfan-Diamond anemia
• Dyskeratosis congenital
• Fanconi anemia
• Myelofibrosis
• Amegakaryocytic thrombocytopenia (AMT)
• Kostmann's syndrome

Immunodeficiencies

• Chronic granulomatous disease
• Common variable immune deficiency (CVID)
• Omenn's syndrome
• Severe combined immune deficiency (SCID and SCID-ADA)
• Reticular dysgenesis
• Thymic dysplasia
• Wiskott-Aldrich syndrome
• X-linked lymphoproliferative disease
• Bare lymphocyte syndrome (MHC class II deficiency)
• Leukocyte adhesion deficiency

Inborn Errors of Metabolism

• Adrenoleukodystrophy
• Batten disease (inherited neuronal ceroid lipofuscinosis)
• Gunther disease
• Hunter syndrome
• Hurler syndrome
• Krabbe disease (globoid cell leukodystrophy)
• Lesch-Nyhan disease
• Maroteaux-Lamy syndrome
• Tay-Sachs disease

* Although the potential use of Umbilical Cord Blood is expanding rapidly, the odds that a family without a defined risk will need to use their child's cord blood are low. There is no guarantee that the umbilical cord blood will be a match for a family member or will provide a cure. As with any transplant therapy, therapeutic success depends upon many factors beyond the stem cells themselves including patient condition, type of disease, recipient-donor relationship matching, and other factors.

HealthyMe.md

Date Published: 2005-02-22

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